Identification of Ethyl Acetate Fraction of 70% Ethanol Extract of Glodokan Tiang Leaf (Polyalthia longifolia (Sonn.) Thwaites)
Keywords: degenerative diseases; cancer; antioxidants; glodokan tiang
AbstractCurrent technological advances, have an impact on changing people's unhealthy life patterns, which can cause degenerative diseases such as cancer. One of them is caused by free radicals, which can cause oxidative stress, which is an imbalance condition between free radicals and antioxidants, one way to overcome oxidative stress is by adding antioxidant compounds. Compounds that have properties as natural antioxidants are flavonoids, alkaloids, and tannins. Glodokan tiang is one of the plants reported to contain these compounds, in the leaves there is a strong activity of antioxidant compounds. This study aims to identify the compounds contained in the ethyl acetate fraction of glodokan tiang leaves, fractionation is carried out to separate compounds with solvents based on the level of polarity in ethyl acetate fraction samples. This research is an experimental study, which is to know the compounds contained in samples of ethyl acetate fraction of 70% glodokan tiang ethanol extract. A sampling of glodokan tiang leaves was carried out by a drying process that had previously been sorted first, the drying process using sunlight and an oven at a temperature of 105C and extraction using 70% ethanol, after that the extract was fractionated using ethyl acetate and then carried out a compound identification test.