PATTERNS OF BACTERIAL RESISTANCE AND SENSITIVITY TO ANTIBIOTICS IN PATIENTS WITH URINARY TRACT INFECTION AT “X” REGIONAL HOSPITAL IN 2024

  • Nachma Vania Sabina S Universitas Pekalongan
  • Ekanita Desiani Universitas Pekalongan
Keywords: antibiotics, bacteria, UTI, resistance, sensitivity

Abstract

Urinary tract infection (UTI) is a condition caused by the presence of microorganisms in very large numbers in the urine and causes infections in the urinary tract. Bacterial resistance to antibiotics reduces the effectiveness of therapy. Bacterial sensitivity aims to determine whether the bacteria are resistant to various antibiotic preparations. The purpose of this study was to determine bacterial resistance and sensitivity in determining the effectiveness of antibiotics in UTI patients. This study research design used being descriptive observational through a design approach retrospective, to see the suitability of antibiotic use and bacterial sensitivity presentation data. Sampling using purposive sampling technique many as 40 samples based on information from medical records of UTI patients at “X” Regional Hospital then analyzed using SPSS and Microsoft Excel. The results of this study found UTI as the main diagnosis of 60% and 40% as a secondary diagnosis. The bacteria that cause UTI in this study were found to be 3 types of bacteria, the most dominant of which are Escherichia coli’s many as 20 patients (50%), Streptococcus sp many as 12 patients (30%) and Acinetobacter baumanniias many as 8 patients (20%). Escherichia coli resistant to the antibiotic cefixime (100%) and most sensitive to the antibiotic ciprofloxacin (100%). Streptococcus spresistant to the antibiotic cefixime (83%) and most sensitive to the antibiotic’s gentamicin and meropenem (92%). Acinobacter baumanniiresistant to the antibiotic cefixime as many as 5 people (62.5%) and most sensitive to the antibiotic trimethoprim-sulfamethoxazole as many as 7 people (87.5%)