Community-acquired pneumonia (CAP) is the 3rd largest lower respiratory tract infection that
causes death in the world. Treatment therapy that is generally used to treat pneumonia is by
administering antibiotics. Irrational use of antibiotics can lead to less effective treatment,
decreased drug safety, and increased resistance. This study aims to evaluate the rationality of
using antibiotics in community-acquired pneumonia patients at UNS Hospital using the Gyssens
method in 2021-2022. This research is a non-experimental research with a descriptive design and
purposive sampling technique. Data collection was carried out retrospectively with a sample size
of 19 patients who were hospitalized in 2021-2022. The data obtained were analyzed descriptively
with the Gyssens assessment. The references used are Regulation of the Minister of Health
Republic Indonesia Number 28, 2021 concerning Guidelines for the Use of Antibiotics,
Guidelines for the Diagnosis of Community Pneumonia and Its Management in Indonesia 2014,
UNS Hospital Drug Formulary, NICE Public Health Guidance 2022, and Dipiro 2020. The
results of this study showed that 90.47% of patients received rational antibiotic therapy and
9.53% received irrational antibiotic therapy. Rational antibiotic therapy is an antibiotic that is
included in category 0. The irrational use of antibiotics in this study is an antibiotic that is
included in the IVC category (there are cheaper alternative antibiotics).
