FORMULATION AND PHYSICAL EVALUATION OF CREAM CONTAINING MENIRAN LEAVES (Phyllanthus niruri L.) USING VARIATIONS OF STEARIC ACID AND TRIETHANOLAMINE

Abstrak

Meniran leaves (Phyllanthus niruri L.) have antibacterial activity against Cutibacterium acnes. The aim of this study was to determine whether varying concentrations of stearic acid and triethanolamine as emulsifiers could affect the physical properties of meniran leaf extract cream formulations (Phyllanthus niruri L.) and to identify the optimal cream formulation. This was an experimental study. The cream formulation was prepared in three formulas with varying concentrations of stearic acid and triethanolamine, namely F1 (15% : 4%), F2 (16% : 3%), and F3 (17% : 2%). The evaluation of the cream formulations included organoleptic properties, pH, homogeneity, viscosity, spreadability, adhesion, irritation, and hedonic properties, as well as data analysis using the One-Way ANOVA method. The results of the analysis showed that variations in stearic acid and triethanolamine concentrations affected spreadability, adhesion, viscosity, and pH values. The best formula was F3 with stearic acid and triethanolamine concentrations of 17% : 2%.