FORMULATION OF EXTRACT MOISTURIZING CREAM WATERMELON (Citrullus lanatus (Thunb.) Matsum. & Nakai) AS ANTIOXIDANT
Dessy Erliani Mugita Sari
Itekes Cendekia Utama Kudus
Devia Damayanti
Itekes Cendekia Utama Kudus
Luvita Gabriel Zulkarya
Farmasi Itekes Cendekia Utama Kudus
Abstrak
Dry skin is one of the most common problems, where dry skin looks dull and rough. Therefore,
it is necessary to prepare a moisturizing cream that can be obtained from watermelon
(Citrullus lanatus (Thunb.) Matsum. & Nakai) which has antioxidant activity in the form of
flavonoids. This studi aims to formulate the watermelon extract (Citrullus lanatus (Thunb.)
Matsum. & Nakai) into fresh cream preparations of watermelon extract (Citrullus lanatus
(Thunb.) Matsum. & Nakai) as antioxidants with varying concentrations of F1 (base), F2 (5%),
and F4 (15%). This type of research is experimental with a post test design with control with
group design. The sample is Watermelon purchased at the Jepara Mayong Market. This
research process uses water extract, namely fresh fruit juice thickened with a water bath
thermostat at a temperature of 80⁰C. Determination of antioxidant activity was carried out
using UV-Vis spectrophotometry using the DPPH (1,1-diphenyl-2-picrylhidrazil) method using
quercetin as a comparison solution. Phytochemical screening of watermelon extract (Citrullus
lanatus (Thunb.) Matsum. & Nakai) was positive for flavonoids, saponons and sucrose. The
content of watermelon extract used for the antioxidant activity test was flavonoids.
Watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai) fruit extract has moderate
antioxidant activity with an IC50 of 143,93 µg/ml. formulated into a moisturizing cream has
weak antioxidant activity IC50 at F1, F2, F3, and F4 respectively 552,09 µg/ml, 451,50 µg/ml
and 387,26 µg/ml. The study shows that watermelon extract (Citrullus lanatus (Thunb.)
Matsum. & Nakai) has moderate antioxidant activity and can be formulated into a
moisturizing cream for watermelon extrac