FORMULATION OF EXTRACT MOISTURIZING CREAM WATERMELON (Citrullus lanatus (Thunb.) Matsum. & Nakai) AS ANTIOXIDANT

  • Dessy Erliani Mugita Sari Itekes Cendekia Utama Kudus
  • Devia Damayanti Itekes Cendekia Utama Kudus
  • Luvita Gabriel Zulkarya Farmasi Itekes Cendekia Utama Kudus

Abstrak

Dry skin is one of the most common problems, where dry skin looks dull and rough. Therefore, it is necessary to prepare a moisturizing cream that can be obtained from watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai) which has antioxidant activity in the form of flavonoids. This studi aims to formulate the watermelon extract (Citrullus lanatus (Thunb.) Matsum. & Nakai) into fresh cream preparations of watermelon extract (Citrullus lanatus (Thunb.) Matsum. & Nakai) as antioxidants with varying concentrations of F1 (base), F2 (5%), and F4 (15%). This type of research is experimental with a post test design with control with group design. The sample is Watermelon purchased at the Jepara Mayong Market. This research process uses water extract, namely fresh fruit juice thickened with a water bath thermostat at a temperature of 80⁰C. Determination of antioxidant activity was carried out using UV-Vis spectrophotometry using the DPPH (1,1-diphenyl-2-picrylhidrazil) method using quercetin as a comparison solution. Phytochemical screening of watermelon extract (Citrullus lanatus (Thunb.) Matsum. & Nakai) was positive for flavonoids, saponons and sucrose. The content of watermelon extract used for the antioxidant activity test was flavonoids. Watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai) fruit extract has moderate antioxidant activity with an IC50 of 143,93 µg/ml. formulated into a moisturizing cream has weak antioxidant activity IC50 at F1, F2, F3, and F4 respectively 552,09 µg/ml, 451,50 µg/ml and 387,26 µg/ml. The study shows that watermelon extract (Citrullus lanatus (Thunb.) Matsum. & Nakai) has moderate antioxidant activity and can be formulated into a moisturizing cream for watermelon extrac